Leptospirosis is an infectious disease of humans and animals that is caused by pathogenic spirochetes of the genus leptospira. It is considered the most common zoonosis in the world and is associated with settings of poor sanitation and agricultural occupations involving contact with animals or water. Affected reservoir species experience tonic colonization of proximal renal tubules and shed leptospires in urine. Humans are not typically considered reservoirs but may chronically shed leptospires and may act as reservoirs in areas of high endemicity and poor waste sanitation Pre-experimental one group pre-test post-test design was used to assess The effectiveness of a structured teaching program on knowledge regarding leptospirosis and its prevention among agricultural workers in selected rural areas at Mysuru. In view of the nature of the problem and to accomplish the objectives of thestudy, a structured teaching programme was prepared focusing on knowledge regarding leptospirosis and its prevention among agricultural workers at selected rural areas in Mysuru. Reliability (R=0.91) of the tool was tested and validity was ensured in consultation with guides and experts in the field of statistics, pediatrics and nursing. The study was carried out in Hanchya, Rammanahalli village at Mysuru by Non-probability convenient sampling technique, 60agricultural workers were selected. Structured knowledge questionnaire was administered to collect the needed data.

Data was analyzed by using descriptive and inferential statistics. With regard to the knowledge assessment, the mean post test score was 19.57 and pre test score 8.72. Theme and difference between pre-test score and post-test score was 10.85. The computed Paired’t’ value was 20.24and it was significant at5% level. This showed that STP on knowledge regarding to leptospirosis and its prevention among agricultural workers was effective. Therefore the research hypothesis (H1) is accepted, i.e. there is significant difference between mean pre-test and mean post-test knowledge score. This study revealed that the STP on knowledge regarding to leptospirosis and its prevention among agricultural workers was effective.