The use of chemicals has increased dramatically due to the economic development in various sectors including industry, agriculture and transport. It increasing incidents of illness like cancers, birth defects and many more due to the varieties of chemicals exposure through the air, water, food and the soil. One among the most hazardous manufacture is the plastic. It has become a part of every aspect of human living. This study was aimed to assess the effectiveness of effectiveness of video assisted teaching module on the knowledge regarding hazards of plastic use among high school children at govt. high school Akbarpur, Bhopal. A quantitative research approach with a pre-experimental research design with pre and post-test without control group experimental approach was used. Non-probability purposive sampling technique was used and 60 subjects were selected and data were collected through the multiple-choice questionnaire and analyzed by descriptive and inferential statistics. The results of the study have revealed that the comparison between pretest and post-test knowledge made by t-test, t= 1.27 at 0.05 level of significance. The comparison between pretest and post-test knowledge of type of plastic & its hazards made by t-test, t= 2.19 at 0.05 level of significance. The comparison between pretest and post-test knowledge on avoidance of plastic made by t-test, t= 2.27 at 0.05 level of significance. This indicates that the video assisting teaching module was effective in improving the knowledge of high school children regarding hazards of plastic & its use.