Objective: The present study aimed to assess the effectiveness of self-instructional module on knowledge regarding cord blood banking among eligible couples in Jabalpur.

Methodology: Pre-experimental, one group pre-test post-test design was adopted for this study. 50 eligible couples in Jabalpur were selected for this study. A pretest was conducted by using structured knowledge questionnaire and on the same day the Self-instructional module regarding cord blood banking was administered to them. After 7 days, post test was conducted with the same questionnaire for the same group of staff Nurses to assess the effectiveness of SIM.

Results: The mean score in the post test is 31.78 and the mean score in the pretest is 14.54. The calculated value of t is 72.35 which is highly significant. The result undoubtedly confirms that the SIM significantly was effective in improving the knowledge on CBB among the eligible couples.