Introduction: Open drainage system may be major and indispensable problems to be solved today. System and its role in sanitation connected outbreaks evident. Sanitation is outlined by the in keeping with the globe health organization as: sanitation usually refers to the availability of facilities and services for the safe disposal of human excrement and faeces.

Aim: The aim of the study is assess the knowledge on transmission of disease from open drainage system among the community people.

Method: A quantitative approach with descriptive research design was adopted for the present study. A non-equivalent pre-test post-test control quasi experimental research design was used. Purposive sampling techniques were used and sample size is 100. A self – structured questionnaire was used to collect the demographic data and the existing level of knowledge on transmission of disease from open drainage among community people.

Result: This study finding shows that there was a statistically significant association observed between the demographic variable of age of samples, sex, education, occupation, monthly income, socio-economic status, type of family, marital status, availability of toilet facilities, With the level of knowledge at p< 0.05 level.

Conclusion: Vector borne disease being the major health problem in community people are unaware about its first aid at home management and leads to complications. The study was done to assess the knowledge and prevention of vector borne disease among community people.