Methods: Randomised controlled clinical trials were reviewed on Pubmed, ISI Web of Sciences and Google Scholar databases. 7 randomised controlled trials were included in meta-analysis.In order to test existence of heterogeneity, Cochran’s Q test and I2 test statistics were applied. According to heterogeneity of test results, fixed effect and random effects meta-analysis models were used. Hedges’ G test statistics was used to show the common effect between pomegranate and placebo groups in meta-analysis.

Results: When the standardised average difference value of pomegranate and placebo groups was calculated to evaluate the effect of pomegranate on reducing the blood glucose, this value was found to be -0.0322 (95% CI:-0.251 to 0.187). When the standardised average difference value of pomegranate and placebo groups was calculated to evaluate the effect of pomegranate on insulin level, this value was found to be -0.129 (95% CI:-0.408 to 0.151). When the standardised average difference value of pomegranate and placebo groups was calculated to evaluate the effect of pomegranate on HbA1c, this value was found to be 0.250 (95% CI:-0.440 to 0.940).

Conclusions: As a result of this meta-analysis, it was observed that the use of pomegranate was an effective approach in reducing blood glucose and insulin concentration. However, it was determined that the use of pomegranate was not an effective approach on HbA1c value.